Blood Pressure Management in Afferent Baroreflex Failure
نویسندگان
چکیده
منابع مشابه
Afferent baroreflex failure in familial dysautonomia.
BACKGROUND Familial dysautonomia (FD) is due to a genetic deficiency of the protein IKAP, which affects development of peripheral neurons. Patients with FD display complex abnormalities of the baroreflex of unknown cause. METHODS To test the hypothesis that the autonomic phenotype of FD is due to selective impairment of afferent baroreceptor input, we examined the autonomic and neuroendocrine...
متن کاملDiminished baroreflex sensitivity in high blood pressure.
as the millisecond increase in cycle length per mm Hg rise in systolic pressure. The slope is an index of baroreflex sensitivity and was found to have an average value of 12.8 in 18 subjects without hypertension and 2.8 in 12 others with hypertension. When all results were pooled, there was an inverse relationship between the resting mean arterial pressure and slope of the baroreflex regression...
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BACKGROUND Familial dysautonomia (FD) is a rare hereditary disease characterized by loss of afferent autonomic neural fiber signaling and consequent profound impairment of arterial baroreflex function and blood pressure regulation. Whether vascular endothelial dysfunction contributes to defective vasomotor control in this form of afferent autonomic failure is not known. METHODS We assessed bl...
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1. Intra-arterial blood pressure and heart rate were recorded for 24 h in ambulant hospitalized patients of variable age who had normal blood pressure or essential hypertension. Mean 24 h values, standard deviations and variation coefficient were obtained as the averages of values separately analysed for 48 consecutive half-hour periods. 2. In older subjects standard deviation and variation coe...
متن کاملDilemmas of blood pressure management for heart failure prevention.
More than 5.5 million individuals in the United States have heart failure (HF), more than a half-million individuals are diagnosed annually, and more than 1 million HF hospitalizations occur yearly.1 Outcomes remain poor, with approximately 50% of patients dying within 5 years of diagnosis.2 These trends will worsen when aging of the 78 million baby boomers will result in 1 in 5 Americans to be...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2019
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2019.10.027